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Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II.

机译：使用小分子抑制剂LY2157299和针对TGF-β受体II型的D10单克隆抗体对HCC细胞中TGF-β信号通路的差异抑制。

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Francesco Dituri; Antonio Mazzocca; Joan Fernando; Patrizia Papappicco; Isabel Fabregat; Flavia De Santis; Angelo Paradiso; Carlo Sabbà; Gianluigi Giannelli;
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1. PTGF-β, a type β transforming growth factor (TGF-β) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF- β signaling pathway [J] . Mingjia Tan, Yixin Wang, Kunliang Guant Proceedings of the National Academy of Sciences of the United States of America . 2000,第1期

机译：PTGF-β是β型转化生长因子（TGF-β）的超家族成员，是p53靶基因，可通过TGF-β信号通路抑制肿瘤细胞的生长
2. TβRIII independently binds type I and type II TGF-β receptors to inhibit TGF-β signaling [J] . Keren Tazat, Melissa Hector-Greene, Gerard C. Blobe, Molecular biology of the cell . 2015,第19期

机译：TβRIII独立结合I型和II型TGF-β受体以抑制TGF-β信号传导
3. The type III TGF-β receptor signals through both Smad3 and the p38 MAP kinase pathways to contribute to inhibition of cell proliferation [J] . Hye Jin You1 Monique W. Bruinsma1 Tam How1 Julie H. Ostrander1 and Gerard C. Blobe12 Carcinogenesis . 2007,第12期

机译：III型TGF-β受体通过Smad3和p38 MAP激酶途径发出信号，从而有助于抑制细胞增殖
4. Chapter 73 Sonic Hedgehog Signaling Molecules Expression in TGF-β1-Induced Chondrogenic Differentiation of Rat Mesenchymal Stem Cells In Vitro [C] . Yingchao Shi, Ying Jia, Shanshan Zu, International symposium on IT in medicine and education . 2014

机译：第73章声波刺猬信号分子在TGF-β1诱导的大鼠间充质干细胞软骨分化中的表达
5. Evaluation of the TGF-β inhibitor RepSox on the expression of pluripotency pathways in murine and bovine cells [D] . Larsen, Davin M. 2013

机译：TGF-β抑制剂Refsox对小鼠和牛细胞多能性途径表达的评价
6. Correction: Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II [O] . -1

机译：校正：使用小分子抑制剂LY2157299和抗TGF-βII型D10单克隆抗体的HCC细胞中TGF-β信号通路的差异抑制
7. Differential inhibition of the TGF-b signaling pathway in HCC cells using the small molecule inhibitor LY2157299 and the D10 monoclonal antibody against TGF-β receptor Type II [O] . Dituri Francesco, Mazzocca Antonio, Peidrò Fernando Juan, 2016

机译：使用小分子抑制剂LY2157299和针对TGF-β受体II型的D10单克隆抗体对HCC细胞中TGF-b信号通路的差异抑制

Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II.

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